Systemic Markers of Lung Function and Forced Expiratory Volume in 1 Second Decline across Diverse Cohorts

Author:

Ngo Debby12ORCID,Pratte Katherine A.3,Flexeder Claudia456,Petersen Hans7,Dang Hong8,Ma Yanlin9,Keyes Michelle J.1,Gao Yan106,Deng Shuliang1,Peterson Bennet D.1,Farrell Laurie A.1,Bhambhani Victoria M.1,Palacios Cesar1,Quadir Juweria1,Gillenwater Lucas3,Xu Hanfei11,Emson Claire12,Gieger Christian413,Suhre Karsten14,Graumann Johannes15,Jain Deepti16,Conomos Matthew P.16,Tracy Russell P.17,Guo Xiuqing18,Liu Yongmei19,Johnson W. Craig16,Cornell Elaine17,Durda Peter17,Taylor Kent D.18,Papanicolaou George J.20,Rich Stephen S.9,Rotter Jerome I.18,Rennard Steven I.21,Curtis Jeffrey L.22,Woodruff Prescott G.21,Comellas Alejandro P.23ORCID,Silverman Edwin K.24,Crapo James D.3,Larson Martin G.1125,Vasan Ramachandran S.252627,Wang Thomas J.2829,Correa Adolfo3010,Sims Mario3010,Wilson James G.130,Gerszten Robert E.131,O’Connor George T.2532,Barr R. Graham3334,Couper David8,Dupuis Josée11,Manichaikul Ani9,O’Neal Wanda K.8,Tesfaigzi Yohannes735ORCID,Schulz Holger45,Bowler Russell P.3ORCID

Affiliation:

1. Cardiovascular Research Institute,

2. Division of Pulmonary, Critical Care, and Sleep Medicine, and

3. National Jewish Health, Denver, Colorado;

4. Institute of Epidemiology and

5. Comprehensive Pneumology Center Munich (CPC-M) as member of the German Center for Lung Research (DZL), Munich, Germany;

6. Institute and Clinic for Occupational, Social, and Environmental Medicine, University Hospital, Ludwig-Maximilians-University, Munich, Germany

7. Lovelace Respiratory Research Institute, Albuquerque, New Mexico;

8. University of North Carolina at Chapel Hill, Chapel Hill, North Carolina;

9. Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia;

10. Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi; and

11. Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts;

12. Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland;

13. Research Unit of Molecular Epidemiology, Helmholtz Zentrum München – German Research Center for Environmental Health, Neuherberg, Germany;

14. Department of Physiology and Biophysics, Weill Cornell Medicine Qatar, Education City, Doha, Qatar;

15. Philipps-Universität, Marburg, Germany;

16. Department of Biostatistics, University of Washington, Seattle, Washington;

17. Department of Pathology and Laboratory Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont;

18. The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA (University of California, Los Angeles) Medical Center, Torrance, California;

19. Division of Cardiology, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina;

20. National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland;

21. Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California, San Francisco, San Francisco, California;

22. University of Michigan, Ann Arbor, Michigan;

23. University of Iowa, Iowa City, Iowa;

24. Channing Division of Network Medicine, and

25. The National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts;

26. Division of Preventive Medicine and

27. Division of Cardiology, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts;

28. Department of Medicine, UT (University of Texas) Southwestern Medical Center, Dallas, Texas;

29. Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee;

30. Jackson Heart Study, Department of Medicine, and

31. Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts;

32. Pulmonary Center, Department of Medicine, Boston University, Boston, Massachusetts;

33. Department of Medicine and

34. Department of Epidemiology, Columbia University, New York, New York;

35. Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts;

Funder

National Institutes of Health

State of New Mexico

German Federal Ministry of Education and Research

Novartis

Publisher

American Thoracic Society

Subject

Pulmonary and Respiratory Medicine

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