1. Department of Critical Care Medicine and
2. Interdepartmental Division of Critical Care Medicine,
3. Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health,
4. Epidemiology Division, Dalla Lana School of Public Health, and
5. Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada;
6. ICES, Toronto, Ontario, Canada;
7. Institute for Better Health, Trillium Health Partners, Mississauga, Ontario, Canada;
8. Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada;
9. Schulich Heart Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada;
10. Division of Critical Care, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; and
11. Lawson Health Research Institute, London, Ontario, Canada