Application of Ion-Exchange Resin Column for Basic Development of Strontium-90/Yttrium-90 Generator for Preparation of Radiopharmaceutical Therapy
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Published:2017-04-01
Issue:1
Volume:17
Page:15
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ISSN:2460-1578
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Container-title:Indonesian Journal of Chemistry
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language:
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Short-container-title:Indones. J. Chem.
Author:
Muchtaridi Muchtaridi,Kamal Elvan,Subarnas Anas,Mutalib Abdul
Abstract
The aim of this study is to examine the possible use of ion-exchange resin on Dowex AG 50x8 in separating Y-90 from Sr-90 which then could be applied in the basic of manufacture of producing Sr-90/Y-90 generator for the production of radiopharmaceutical cancer therapy. The findings showed that a distributive coefficient of Sr-90 and Y-90 with HCl 6 N solvent showed that distributive coefficient of Sr-90 in cation-exchange resin on Dowex 50x8 was greater than Y-90. Y-90 in HCl 6 N solvent was more easily eluted, while Sr-90 was bound to resin.. In conclusion, resin on Dowex AG 50x8 with HCl 6 N elution solvent might be able to separate Y-90 from Sr-90 as the basis for Sr-90/Y-90 generator.
Publisher
Universitas Gadjah Mada
Subject
General Chemistry
Cited by
1 articles.
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