Tacrolimus Dosing in Pediatric Heart Transplant Patients is Related to CYP3A5 and MDR1 Gene Polymorphisms-Reference-Cited by-同舟云学术

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Tacrolimus Dosing in Pediatric Heart Transplant Patients is Related to CYP3A5 and MDR1 Gene Polymorphisms

Published:2003-04 Issue:4 Volume:3 Page:477-483
ISSN:1600-6135
Container-title:American Journal of Transplantation
language:en
Short-container-title:

Author:

Zheng HongXia,Webber Steven,Zeevi Adriana,Schuetz Erin,Zhang Jiong,Bowman Pamela,Boyle Gerard,Law Yuk,Miller Susan,Lamba Jatinder,Burckart Gilbert J.

Publisher

Wiley

Subject

Pharmacology (medical),Transplantation,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1034/j.1600-6143.2003.00077.x/fullpdf

Reference45 articles.

1. Tacrolimus is a class II low-solubility high-permeability drug. the effect of P-glycoprotein efflux on regional permeability of tacrolimus in rats;Tamura;J Pharm Sci,2002;

2. Effect of intestinal P-glycoprotein on daily tacrolimus trough level in a living-donor small bowel recipient;Masuda;Clin Pharmacol Ther,2000

3. Effects of intestinal and hepatic metabolism on the bioavailability of tacrolimus in rats;Hashimoto;Pharm Res,1998

4. Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug delivery;Benet;J Control Release,1999

5. Overlapping substrate specificities and tissue distribution of cytochrome P450, 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy;Wacher;Mol Carcinog,1995

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