SYNTHESIS OF α- HYDROXY-β, γ-UNSATURATED ESTERS

Author:

Jarugu Lokesh Babu1,D. Vankar Yashwanth2,Brar Anita3

Affiliation:

1. Syngene International (India)

2. Indian Institute of Technology, Kanpur

3. Govt. College of Engineering and Technology (Jammu - India)

Abstract

α-hydroxy-β, γ-unsaturated esters are important building blocks of bioactive compounds, natural products, achiral and chiral vinyl epoxides. These could be easily obtained by isomerization of glycidic esters. In this paper we have reported easy and convenient way of synthesis of α-hydroxy-β, γ-unsaturated esters by isomerisation of glycidic esters using inexpensive catalyst HClO4-SiO2 and eco-friendly ionic liquid. Moderate to good yields with lower reaction times reported.

Publisher

International Association of Research Scholars

Subject

General Medicine

Reference22 articles.

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