A HERBAL TREATMENT METHOD FOR BREAST CANCER: ANTITUMOR EFFECT OF MOMORDICA CHARANTIA

Author:

Ihlamur Murat1ORCID,Kelleci Kübra2ORCID,Özkan Melisa3ORCID,Abamor Emrah Şefik2ORCID

Affiliation:

1. BİRUNİ ÜNİVERSİTESİ

2. YILDIZ TEKNİK ÜNİVERSİTESİ

3. YILDIZ TECHNICAL UNIVERSITY

Abstract

Using plant-based treatment approaches and herbal medicines is getting attention these days to avoid the side effects of the current treatment methods for cancer. According to the literature, bitter melon extract exhibits cytotoxic effects against cancer by affecting the hormonal pathways. Therefore, in this research, the effects of the bitter melon extract with its combination of different concentrations of drugs were investigated against different cell lines (MCF-7, MDA-MB-231, RAW 264.7, J774). Both hormone-positive and negative breast cancer cell lines were used and the obtained data were compared with the literature. As a result, when exposed to bitter melon extract, the hormone-positive breast cancer cell line MCF-7 exhibits more cytotoxic effects compared to the triple hormone-negative breast cancer cell line MDA-MBA-231. For the combination of drugs along with the bitter melon extract; the highest cytotoxicity was observed with Tamoxifen.

Publisher

Istanbul Ticaret Universitesi

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3