Influence of glucocorticoid hormones on the thyroid gland function

Author:

Gusakova E. A.1ORCID,Gorodetskaya I. V.1ORCID

Affiliation:

1. Vitebsk State Order of Peoples’ Friendship Medical University

Abstract

The injection of exogenous analogues of glucocorticoid hormones (cortisone, hydrocortisone, corticosterone, dexamethasone, betamethasone, etc.) leads to a change in thyroid function at all levels (biosynthesis and secretion of hormones by the thyroid gland, the transport, interaction with receptors in target organs, biological action, their metabolism and excretion). Glucocorticoid hormones change regulationof the thyroid function: transhypophysially (glucocorticoids block the secretion of thyroliberin, thyroid stimulating hormone, corticotropin releasing hormone, somatoliberin and the production of somatotropin under the influence of the last one) and parahypophysially (glucocorticoids stimulate formation of insulin in β-cells of the pancreas).

Publisher

Publishing House Belorusskaya Nauka

Subject

General Medicine

Reference37 articles.

1. Kuznetsov E. V., Zhukova L. A., Pakhomova E. A., Gulamov A. A. Endocrine diseases as a medical-social problem of modernity. Sovremennye problem nauki i obrazovaniya [Modern problems of science and education], 2017, no. 4, p. 62 (in Russian).

2. Gorodetskaya I. V., Gusakova E. A. The effect of iodine-containing thyroid hormones on the central part of the stresslimiting system. Vestnik Vitebskogo gosudarstvennogo meditsinskogo universiteta [Bulletin of Vitebsk State Medical University], 2018, vol. 17, no. 3, pp. 7–15 (in Russian).

3. Vinogradov V. V., Golyshko P. V., Tumanov A. V., Andreev V. P., Nadol’nik L. I., Yarotskii Yu. V. The effect of glucocorticoids on the morphology and function of the thyroid gland of rats]. Vestsі Natsyyanal’nai akademіі navuk Belarusi. Seryya biyalagіchnykh navuk= Proceedings of the National Academy of Sciences of Belarus. Biological series, 2010, no. 3, pp. 87–93 (in Russian).

4. Martinho A., Gonçalves I., Costa M., Santos C. R. Stress and glucocorticoids increase transthyretin expression in rat choroid plexus via mineralocorticoid and glucocorticoid receptors. Journal of Molecular Neuroscience, 2012, vol. 48, no. 1, pp. 1–13. https://doi.org/10.1007/s12031-012-9715-7

5. Sviridov O. V., Ermolenko M. N. Interaction of thyroid hormones with immunoglobulins isolated from human blood serum. I. Parameters of complex formation and the nature of the binding reaction. Biokhimiia, 1994, vol. 59, no. 1, pp. 78–87. 6. Franco L. M., Gadkari M., How K. N., Sun J., Kardava L., Kumar P. [et al.]. Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses. Journal of Experimental Medicine, 2019, vol. 216, no. 2. pp. 384–406. https://doi.org/10.1084/jem.20180595

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3