Effects of fatty acid amides with ethanolamine and glycine on nociceptive reactions and gait parameters in rats in normal and experimental peripheral mononeuropathy

Author:

Doronkina A. S.1,Mikhalchuk A. L.2,Goubkin S. V.1,Molchanova A. Yu.1,Bogdan V. G.3

Affiliation:

1. Institute of Physiology of the National Academy of Sciences of Belarus

2. Institute of Bioоrganic Chemistry of the National Academy of Sciences of Belarus

3. Department of Medical Sciences of the National Academy of Sciences of Belarus

Abstract

The effects of fatty acid amides ethanolamine and glycine on gait patterns and nociceptive reactions was investigated after injections of these fatty acid derivatives in healthy rats and in rats with experimental peripheral neuropathy. It has been proven that palmitoylethanolamide and the stearoylethanolamide are more effective at relieving neuropathic pain and restoring gait parameters than glycine palmitamide.

Publisher

Publishing House Belorusskaya Nauka

Subject

General Medicine

Reference15 articles.

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