Extraction of amitraz and its metabolites with organic solvents-Reference-Cited by-同舟云学术

Extraction of amitraz and its metabolites with organic solvents

Published:2023-06-05 Issue:2 Volume:59 Page:139-149
ISSN:2524-2342
Container-title:Proceedings of the National Academy of Sciences of Belarus, Chemical Series
language:
Short-container-title:Vescì Akademìì navuk Belarusì. Seryâ himičnyh navuk

Author:

Polonevich A. G¹,Leschev S. M.²,Bulhakava V. A.³,Belysheva L. L.³

Affiliation:

1. Belarusian State University; Scientific Practical Center of Hygiene

2. Belarusian State University

3. Scientific Practical Center of Hygiene

Abstract

The distribution constants of amitraz and its three main metabolites (DMFF, DMF, DMA) for water–organic solvent (n-hexane, toluene, dichloromethane, chloroform) extraction systems were estimated. Based on the analysis of the substances distribution in the studied systems, it was established that dichloromethane is the optimal choice for amitraz and its metabolites liquid-liquid extraction for method development for their simultaneous determination in honey. Amitraz stability study in water-acetonitrile solutions with various additives demonstrated that 50 mM ammonia solution in water– acetonitrile mixture (1 : 1, vol.) should be used as solvent for the samples final solutions.

Publisher

Publishing House Belorusskaya Nauka

Subject

Inorganic Chemistry,Organic Chemistry,Chemistry (miscellaneous),Analytical Chemistry

Reference25 articles.

1. Gupta R. C. (ed.). Amitraz. Veterinary Toxicology. Basic and Clinical Principles. 3d ed. Academic Press, 2018. pp. 525–531. https://doi.org/10.1016/B978-0-12-811410-0.00041-6

2. Weijia Zheng, Jin-A. Park, A. M. Abd El-Aty, Seong-Kwan Kim, Sang-Hyun Cho, Jeong-min Choi, Hee Yi, Soo-Min Cho, Amer Ramadan, Ji Hoon Jeong, Jae-Han Shim, Ho-Chul Shin. Development and validation of modified QuEChERS method coupled with LC–MS/MS for simultaneous determination of cymiazole, fipronil, coumaphos, fluvalinate, amitraz, and its metabolite in various types of honey and royal jelly. Journal of Chromatography B, 2018, vol. 1072, pp. 60–69. https://doi.org/10.1016/j.jchromb.2017.11.011

3. Jin-Zhong Xu, Jian-Jun Miao, Hong Lin, Tao Ding, Zhen-Yun Zhao, Bin Wu, Chong-Yu Shen, Yuan Jiang. Determination of amitraz and 2,4-dimethylaniline residues in honey by using LC with UV detection and MS/MS. Journal of Separation Science, 2009, vol. 32, iss. 23-24, pp. 4020–4024. https://doi.org/10.1002/jssc.200900437

4. Osano O., Oladimeji A. A., Kraak M. H., Admiraal W. Teratogenic effects of amitraz, 2,4-dimethylaniline, and paraquat on developing frog (Xenopus) embryos. Archives of environmental contamination and toxicology, 2002, vol. 43, pp. 42–49. https://doi.org/10.1007/s00244-002-1132-4

5. Nilgun Tokman, Carla Soler, Marinel la Farré, Yolanda Picó, Damià Barceló. Determination of amitraz and its transformation products in pears by ethyl acetate extraction and liquid chromatography–tandem mass spectrometry. Journal of Chromatography A, 2009, vol. 1216, iss. 15., pp. 3138–3146. https://doi.org/10.1016/j.chroma.2009.01.099