Determination of the hexamethylenediamine impurity in polyhexamethylene guanidine hydrochloride by HPLC method-Reference-Cited by-同舟云学术

Determination of the hexamethylenediamine impurity in polyhexamethylene guanidine hydrochloride by HPLC method

Published:2019-06-29 Issue:2 Volume:55 Page:156-162
ISSN:2524-2342
Container-title:Proceedings of the National Academy of Sciences of Belarus, Chemical Series
language:
Short-container-title:Vescì Akademìì navuk Belarusì. Seryâ himičnyh navuk

Author:

Yurachka V. V.¹,Yuzhik L. I.¹,Tarasevich V. A.¹,Krasilnikov A. A.²,Filonov V. P.²

Affiliation:

1. Institute of Chemistry of New Materials of the National Academy of Sciences of Belarus

2. ZAO «BelAseptika»

Abstract

The object of the study was a polymeric biocidal material – polyhexamethyleneguanidine hydrochloride (PGMG GC). The purpose of this work was to develop a method for the quantitative determination of HMDA in the target synthesis product – PGMG GC by high-performance liquid chromatography (HPLC). Analytical data obtained during the assessment of the system’s precision, specificity, precision, accuracy and linearity of the method corresponded to the established acceptance criteria. The proposed analytical method of HMDA determination in polymeric PGMG GC is validated with respect to the indicated parameters and can be used to determine the HMDA content in the range 0,75–0,025 %.

Publisher

Publishing House Belorusskaya Nauka

Subject

Inorganic Chemistry,Organic Chemistry,Chemistry (miscellaneous),Analytical Chemistry

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