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New lipophilic conjugates of fluorescent NBD-piperazine: synthesis, in silico interactions with lipid bilayer and cytochromes P450

  • Published:2022-03-10 Issue:1 Volume:58 Page:62-67
  • ISSN:2524-2342
  • Container-title:Proceedings of the National Academy of Sciences of Belarus, Chemical Series
  • language:
  • Short-container-title:Vescì Akademìì navuk Belarusì. Seryâ himičnyh navuk

Author:

Faletrov Y. V.1,Pozniak H. I.2,Yakovets P. S.2,Frolova N. S.1,Shkumatov V. M.1

Affiliation:

1. Belarusian State University; Research Institute for Physical Chemical Problems of the Belarusian State University

2. Belarusian State University

Publisher

Publishing House Belorusskaya Nauka

Subject

Inorganic Chemistry,Organic Chemistry,Chemistry (miscellaneous),Analytical Chemistry

Reference6 articles.

1. Ishiguro K., Ando T., Goto H. Novel application of 4-nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole to visualize lysosomes in live cells. Biotechniques, 2008, vol. 45, pp. 467–468. https://doi.org/10.2144/000112912

2. Fan J., Han Z., Kang Y., Peng X. A Two-Photon Fluorescent Probe for Lysosomal Thiols in Live Cells and Tissues. Scientific Reports, 2016, vol. 6, pp. 19562. https://doi.org/10.1038/srep19562

3. Xu Z., Wu Z., Tan H., Yan J., Liu X., Li J., Xu Z., Dong C., Zhang L. Piperazine-tuned NBD-based colorimetric and fluorescent turn-off probes for hydrogen sulfide. Analytical Methods, 2018, vol. 10, pp. 3375–3379. https://doi.org/10.1039/C8AY00797G

4. Faletrov Y. V., Karpushenkova V. S., Zavalinich V. A., Yakovets P. S., Shkredava A. D., Shkumatov V. M. Interaction of nitrobenzoxadiazole derivatives of piperazine and aniline with bovine serum albumine in silico and in vitro. Zhurnal Belorusskogo gosudarstvennogo universiteta. Khimiya = Journal of the Belarusian State University. Chemistry, 2021, no. 2, pp. 25–35 (in Russian). https://doi.org/10.33581/2520-257X-2021-2-25-35

5. Faletrov Y. V., Gilep K. A., Falchevskaya A. S., Horetski M. S., Panada J. V., Andrievskaya E. V., Rudaya E. V., Frolova N. S., Brzostek A., Plocinska R., Shkumatov V. M. In silico modeling of izoniazid-steroid conjugates interactions with cytochromes P450 of mycobacteria and their bioconversion in vitro by the cells. Biomeditsinskaya Khimiya, 2020, vol. 66, no. 5, pp. 378–385 (in Russian). https://doi.org/10.18097/PBMC20206605378
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