Estimation of the selectivity of sorbents for IgG binding based on tripeptide ligands-Reference-Cited by-同舟云学术

Estimation of the selectivity of sorbents for IgG binding based on tripeptide ligands

Published:2021-07-16 Issue:3 Volume:65 Page:303-308
ISSN:2524-2431
Container-title:Doklady of the National Academy of Sciences of Belarus
language:
Short-container-title:Dokl. Akad. nauk

Author:

Pustsyulga Y. S.¹,Gribovskaya O. V.¹,Ermola E. M.¹,Golubovich V. P.¹,Moiseenok A. G.²

Affiliation:

1. Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus

2. Institute of Biochemistry of Biologically Active Compounds of the National Academy of Science of Belarus

Abstract

Biospecific sorbents for the removal of IgG and subclasses from biological fluids based on oligopeptides, containing aromatic amino acid residues, were created. The selectivity properties of specific sorbents for IgM, IgE, and plasma proteins were evaluated. It was found that the created sorbents exhibit the low activity to the total plasma protein, albumin, IgM, IgE and are highly specific for IgG.

Publisher

Publishing House Belorusskaya Nauka

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