Predictive significance of a complex approach in determining the vascular wall stiffness parameters in patients with arterial hypertension and in patients with arterial hypertension after ischemic stroke-Reference-Cited by-同舟云学术

Predictive significance of a complex approach in determining the vascular wall stiffness parameters in patients with arterial hypertension and in patients with arterial hypertension after ischemic stroke

Published:2022-11-03 Issue:5 Volume:66 Page:525-532
ISSN:2524-2431
Container-title:Doklady of the National Academy of Sciences of Belarus
language:
Short-container-title:Dokl. Akad. nauk

Author:

Kindaliova V. G.¹,Pronko T. P.¹,Dobrodey M. A.¹,Gubkin S. V.²

Affiliation:

1. Grodno State Medical University

2. Institute of Physiology of the National Academy of Sciences of Belarus

Abstract

The article presents the information about the predictive significance of a complex approach in determining vascular wall stiffness parameters. A total of 159 people with arterial hypertension (AH) and AH after a previous ischemic stroke were examined. A model with a conditional linear predictor (LP) was constructed, using a binary regression equation with a probit-link function for prediction of cardiovascular events. LP is a combination of indicators such as age (А), glomerular filtration rate (CKD-EPI), pulse wave velocity (PWV), intima- media thickness (IMT), cardio-ankle vascular index (CAVI) and augmentation index (AI). The equation has the following form: LP = –6.6139 – 0.0978A + 0.031CKDEPI + 0.0758PWV + 3.2086IMT + 0.4421CAVI + 1.2429AI. The cut-off threshold for LP = 0.0238, sensitivity (Se) 85.71 %, specificity (Sp) 77 % and accuracy (Acc) 78.07 %.

Publisher

Publishing House Belorusskaya Nauka

Subject

General Medicine

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