Characteristics of the severity of the early formation of the atherosclerotic process in certain pathological forms of coronary heart disease in marine specialists in the conditions of the Arctic region

Author:

Zakrevsky Yu. N.1,Gertsev A. V.2ORCID

Affiliation:

1. Murmansk Arctic University

2. 1469 Naval Clinical Hospital, Ministry of Defence of the Russian Federation

Abstract

The present work aims to study lipid balance, specifi markers of atherosclerosis, morphological changes in the main arteries, as well as paired indicators, in the formation of the atherosclerotic process in some non-comorbid pathological forms (painful/silent episodes of angina pectoris) of chronic coronary artery disease occurring with affective disorders in shipboard personnel serving in the Far North. The study revealed a higher incidence of structural changes in the medial sheath of both common carotid arteries in silent angina pectoris, which are manifested in vascular bed remodeling, formation of atherosclerotic plaques, and stenotic atherosclerosis. In addition, an increase in proatherogenic activity, suppression of antiatherogenic parameters, as well as more significant changes in the paired indicators of the atherosclerotic process were observed in such patients. The exacerbation of the main pathological process in chronic coronary artery disease can be attributed to the existing polymorbidity.

Publisher

FSEI HPE Murmansk State Technical University

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