Organosilicon polymer for the release of antimicrobial drugs
Author:
Sarraj SaraORCID,
Szymiczek MałgorzataORCID
Abstract
An organosilicon polymer was developed for the release of antimicrobial drugs. The influence of the drug itraconazole (Itrax) on polymer properties such as density, hardness, rebound resilience, tensile strength, accelerated aging, structure and antifungal activity was investigated. There were slight changes in physicochemical properties and significant deterioration of mechanical ones. The evaluation of the fungicidal activity showed time-limited antifungal properties.
Publisher
LUKASIEWICZ Research Network - Industrial Chemistry Research Institute
Subject
Materials Chemistry,Polymers and Plastics,General Chemical Engineering