Drug Interactions and Side Effects of Co-Administration of Chloroquine/Hydroxychloroquine and Azithromycin: on the Issue of Rational Pharmacotherapy of Patients with COVID-19 with Antimalarial Drugs

Author:

Gaisenok O. V.1

Affiliation:

1. United Hospital with Outpatient Department, Administrative Department of the President of the Russian Federation

Publisher

Stolichnaya Izdatelskaya Kompaniyaizdat

Subject

Pharmacology (medical),Cardiology and Cardiovascular Medicine

Reference44 articles.

1. Grasselli G., Zangrillo A., Zanella A., et al. COVID-19 Lombardy ICU Network. Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy. JAMA. 2020;323(16):1574-81. DOI:10.1001/jama.2020.5394.

2. Temporary methodical recommendations. Prevention, diagnostics and treatment of new coronaviral infection (COVID-19). Version 5. 08.04.2020 [cited by Apr 15, 2020]. Available from: https://sta-tic-1.rosminzdrav.ru/system/attachments/attaches/000/049/951/original/09042020_%D0%9C%D0%A0_COVID-19_v5.pdf (In Russ.)

3. Gautret F., Lagier J.C., Parola P., et al. Hydroxychloroquine and azithromycin as a treatment of COVID19: results of an open label non-randomized clinical trial. Int J Antimicrob Agents. 2020 Mar 20;105949. DOI:10.1016/j.ijantimicag.2020.105949.

4. Plantone D., Koudriavtseva T. Current and Future Use of Chloroquine and Hydroxychloroquine in Infectious, Immune, Neoplastic, and Neurological Diseases: A Mini-Review. Clin Drug Investig. 2018;38(8):653-71. DOI:10.1007/s40261-018-0656-y.

5. Chloroquine (Chloroquinum). Instructions for use of the drug [cited by Apr 15, 2020]. Available from: http://grls.rosminzdrav.ru/Grls_View_v2.aspx?routingGuid=3a670ed0-fd8c-43f6-9001-46d752ea1a4e&t= (In Russ.)

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