The PROTAC selectively degrading Bcl-x<sub>L</sub> represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while sparing bone growth-Reference-Cited by-同舟云学术

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The PROTAC selectively degrading Bcl-x_L represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while sparing bone growth

Published:2022 Issue:17 Volume:12 Page:7476-7490
ISSN:1838-7640
Container-title:Theranostics
language:en
Short-container-title:Theranostics

Author:

Zhang Shaoqing,Chen Yue,Xu Zhongli,Yang Jun,Sun Renhong,Wang Juan,Sun Yiming,Jiang Biao,Yang Xiaobao,Tan Wenfu

Publisher

Ivyspring International Publisher

Subject

Pharmacology, Toxicology and Pharmaceutics (miscellaneous),Medicine (miscellaneous)

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Sorafenib and SIAIS361034, a novel PROTAC degrader of BCL-xL, display synergistic antitumor effects on hepatocellular carcinoma with minimal hepatotoxicity;Biochemical Pharmacology;2024-09

2. Synthesis of selective BCL-XL PROTAC and potent antitumor activity in glioblastoma;2024-08-19

3. Discovery of a potent Gilteritinib-based FLT3-PROTAC degrader for the treatment of Acute myeloid leukemia;Bioorganic Chemistry;2024-08

4. A Selective FGFR1/2 PROTAC Degrader with Antitumor Activity;Molecular Cancer Therapeutics;2024-04-22

5. KOR-Based Effect of Smo/Gli1 on the Development of Osteoarthritis Inflammation via Hedgehog (Hh) and Mechanism Study;J BIOL REG HOMEOS AG;2024

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