The Effect of the Peristimulus α Phase on Visual Perception through Real-Time Phase-Locked Stimulus Presentation

Abstract

AbstractThe α phase has been theorized to reflect fluctuations in cortical excitability and thereby impose a cyclic influence on visual perception. Despite its appeal, this notion is not fully substantiated, as both supporting and opposing evidence has been recently reported. In contrast to previous research, this study examined the effect of the peristimulus instead of prestimulus phase on visual detection through a real-time phase-locked stimulus presentation (PLSP) approach. Specifically, we monitored phase data from magnetoencephalography (MEG) recordings over time, with a newly developed algorithm based on adaptive Kalman filtering (AKF). This information guided online presentations of masked stimuli that were phased-locked to different stages of the α cycle while healthy humans concurrently performed detection tasks. Behavioral evidence showed that the overall detection rate did not significantly vary according to the four predetermined peristimulus α phases. Nevertheless, the follow-up analyses highlighted that the phase at 90° relative to 180° likely enhanced detection. Corroborating neural parietal activity showed that early interaction between α phases and incoming stimuli orchestrated the neural representation of the hits and misses of the stimuli. This neural representation varied according to the phase and in turn shaped the behavioral outcomes. In addition to directly investigating to what extent fluctuations in perception can be ascribed to the α phases, this study suggests that phase-dependent perception is not as robust as previously presumed, and might also depend on how the stimuli are differentially processed as a result of a stimulus-phase interaction, in addition to reflecting alternations of the perceptual states between phases.