Abstract
Hippocampal activity linking past experiences and simulations of the future with current goals can play an important role in decision-making. The representation of information within the hippocampus may be especially critical in situations where one needs to overcome past rewarding experiences and exert self-control. Self-control success or failure may depend on how information is represented in the hippocampus and how effectively the representation process can be modified to achieve a specific goal. We test this hypothesis using representational similarity analyses of human (female/male) neuroimaging data during a dietary self-control task in which individuals must overcome taste temptations to choose healthy foods. We find that self-control is indeed associated with the way individuals represent taste information (valance) in the hippocampus and how taste representations there adapt to align with different goals/contexts. Importantly, individuals who were able to shift their hippocampal representations to a larger degree to align with the current motivation were better able to exert self-control when facing a dietary challenge. These results suggest an alternative or complementary neurobiological pathway leading to self-control success and indicate the need to update the classical view of self-control to continue to advance our understanding of its behavioral and neural underpinnings.SIGNIFICANCE STATEMENTThe paper provides a new perspective on what leads to successful self-control at the behavioral and neurobiological levels. Our data suggest that self-control is enhanced when individuals adjust hippocampal processing to align with current goals.
Funder
Swiss national Science Foundation
Moore Foundation and the economic research service of the U.S Department of Agriculture on behavioral health economics research on dietary choice and obesity
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1 articles.
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