Affiliation:
1. HARRAN ÜNİVERSİTESİ, ECZACILIK FAKÜLTESİ
2. HARRAN ÜNİVERSİTESİ
Abstract
Algae are primary producers in the aquatic environment and from an important part of the food chain. Algae have secondary metabolites with high biological activity, which are especially important in the creation of novel pharmaceutical agents. Main purpose of the research was to ascertain antioxidant, anti-alzheimer, anti-diabetic and tyrosinase inhibitory activities of ethanol, hexane and water extracts of some macro/micro algae. Maceration was used as the sample prepatation method. Antioxidant activity of algea for different radical and compound was assessed. Anti-Alzheimer activity of the obtained calluses were determined using Ellman method which is a spectrophotometric method. Anti-diabetic activities were determined using the α-glucosidase inhibition method. It was discovered that the water extract contained more antioxidant phytochemicals, including phenolic (587.54±2.12 mg PEs/g DW) and flavonoids (618.39±2.47 mg QEs/g DW). This study confirmed that the water extract contained high levels of biological acitivty. This extract may be utilized as a possible source of beneficial nutrients or antioxidants.
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