Androgenetic Alopecia: A Study on The Efficacy of a Combined Protocol of Blue Light Photobiomodulation and Subcutaneous Infiltrations of Biomimetic Peptides

Abstract

Androgenetic Alopecia (AGA) is a common condition affecting men and women, characterized by progressive hair follicle miniaturization and consequent hair loss. Blue light Photobiomodulation (PBM) by LED (Light emitting diode) device and infiltrations of biomimetic peptides therapy are two emerging approaches for AGA treatment. The aim of this study was to evaluate the efficacy of a combined protocol of blue light PBM and infiltrations of biomimetic peptides on the scalp for AGA treatment. A total of 20 patients with AGA diagnosis, according to Hamilton-Norwood criteria, were enrolled in the study. All patients were treated at the same time, both with Blue light LED and with subcutaneous infiltrations of biomimetic peptides on the scalp. At 6 months follow-up, a significant increase in hair density was observed in 85% of the patients treated. The results of our study suggest that the combined protocol of blue light PBM and biomimetic PRP could be an effective treatment for AGA. Further clinical studies with a larger number of patients are needed to confirm these results and to evaluate the long-term efficacy of the treatment.