A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis-Reference-Cited by-同舟云学术

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A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis

Published:2010-02 Issue:9 Volume:285 Page:6706-6715
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

He Shaoqing,McPhaul Christopher,Li John Zhong,Garuti Rita,Kinch Lisa,Grishin Nick V.,Cohen Jonathan C.,Hobbs Helen H.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference32 articles.

1. Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity

2. Molecular mediators of hepatic steatosis and liver injury

3. Linkage of a Gene for Familial Hypobetalipoproteinemia to Chromosome 3p21.1-22

4. A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

5. A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity

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1. PPARγ regulates PNPLA3 in adipocytes in vitro and in vivo in healthy obese patients and mice with metabolic dysfunction-associated steatohepatitis;2024-08-09

2. Psoriasis and steatotic liver disease: Are PNPLA3 and TM6SF2 polymorphisms suitable for the hepato-dermal axis hypothesis?;Annals of Hepatology;2024-07

3. Genetic Variations and Nonalcoholic Fatty Liver Disease: Field Synopsis, Systematic Meta-Analysis, and Evidence* *;BIOMED ENVIRON SCI;2024

4. Combination of risk alleles of PNPLA3, TM6SF2, and HSD17B13 of donors can predict recurrence of steatotic liver disease after liver transplantation;Hepatology Research;2024-06-20

5. PNPLA3 is a triglyceride lipase that mobilizes polyunsaturated fatty acids to facilitate hepatic secretion of large-sized very low-density lipoprotein;Nature Communications;2024-06-06

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