Increased Production of Functional Recombinant Human Clotting Factor IX by Baby Hamster Kidney Cells Engineered to Overexpress VKORC1, the Vitamin K 2,3-Epoxide-reducing Enzyme of the Vitamin K Cycle
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference22 articles.
1. Recombinant factor VIIa (NovoSeven®) as a hemostatic agent
2. Human recombinant factor IX: safety and efficacy studies in hemophilia B patients previously treated with plasma-derived factor IX concentrates
3. Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis
4. Blood coagulation and its regulation by anticoagulant pathways: genetic pathogenesis of bleeding and thrombotic diseases
5. Warfarin and the Vitamin K-Dependent γ-Carboxylation System
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1. Mechanism of VKORC1 and VKORC1L1 signaling in the effects of sodium dehydroacetate on coagulation factors in rat hepatocytes;Toxicology in Vitro;2023-03
2. A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase;Nature Communications;2023-02-14
3. Effect of prepropeptide replacement on γ-carboxylation and activity of recombinant coagulation factor IX;Biotechnology Letters;2022-06-22
4. Recent advances in the production of recombinant factor IX: bioprocessing and cell engineering;Critical Reviews in Biotechnology;2022-04-17
5. Calumenin knockdown, by intronic artificial microRNA, to improve expression efficiency of the recombinant human coagulation factor IX;Biotechnology Letters;2022-04-12
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