Probing the Role of Crystallographically Defined/Predicted Hinge-bending Regions in the Substrate-induced Global Conformational Transition and Catalytic Activation of Human Phenylalanine Hydroxylase by Single-site Mutagenesis-Reference-Cited by-同舟云学术

Probing the Role of Crystallographically Defined/Predicted Hinge-bending Regions in the Substrate-induced Global Conformational Transition and Catalytic Activation of Human Phenylalanine Hydroxylase by Single-site Mutagenesis

Published:2004-06 Issue:25 Volume:279 Page:26571-26580
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Stokka Anne Jorunn,Carvalho Raquel Negrão,Barroso João Filipe,Flatmark Torgeir

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference37 articles.

1. PAHdb 2003: What a locus-specific knowledgebase can do

2. Structural Insight into the Aromatic Amino Acid Hydroxylases and Their Disease-Related Mutant Forms

3. Structure of Tetrameric Human Phenylalanine Hydroxylase and Its Implications for Phenylketonuria

4. A simple purification of phenylalanine hydroxylase by substrate-induced hydrophobic chromatography.

5. Substrate activation of phenylalanine hydroxylase. A kinetic characterization.

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