The Stereoselective Targeting of a Specific Enzyme-Substrate Complex Is the Molecular Mechanism for the Synergic Inhibition of HIV-1 Reverse Transcriptase by (R)-(−)-PPO464-Reference-Cited by-同舟云学术

The Stereoselective Targeting of a Specific Enzyme-Substrate Complex Is the Molecular Mechanism for the Synergic Inhibition of HIV-1 Reverse Transcriptase by (R)-(−)-PPO464

Published:2001-11 Issue:48 Volume:276 Page:44653-44662
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Maga Giovanni,Ramunno Anna,Nacci Vito,Locatelli Giada A.,Spadari Silvio,Fiorini Isabella,Baldanti Fausto,Paolucci Stefania,Zavattoni Maurizio,Bergamini Alberto,Galletti Bruno,Muck Sandra,Hubscher Ulrich,Giorgi Gianluca,Guiso Giovanna,Caccia Silvio,Campiani Giuseppe

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference39 articles.

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2. The HIV-1 Reverse Transcription (RT) Process as Target for RT Inhibitors

3. The role of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection1Presented at the Eleventh International Conference on Antiviral Research, San Diego, CA, 5–10 April 1998.1

4. New Developments in the Chemotherapy of Lentivirus (Human Immunodeficiency Virus) Infections: Sensitivity/Resistance of HIV-1 to Non-nucleoside HIV-1-specific Inhibitors.

5. High resolution structures of HIV-1 RT from four RT–inhibitor complexes

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