Coagulation factor VIIa-mediated protease-activated receptor 2 activation leads to β-catenin accumulation via the AKT/GSK3β pathway and contributes to breast cancer progression

Author:

Roy Abhishek,Ansari Shabbir A.,Das Kaushik,Prasad Ramesh,Bhattacharya Anindita,Mallik Suman,Mukherjee Ashis,Sen ProsenjitORCID

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference48 articles.

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2. High affinity Ca2+-binding site in the serine protease domain of human factor VIIa and its role in tissue factor binding and development of catalytic activity;Sabharwal;J. Biol. Chem,1995

3. Biochemistry and physiology of blood coagulation;Mann;Thromb. Haemost,1999

4. Structural modulation of factor VIIa by full-length tissue factor (TF1–263): implication of novel interactions between EGF2 domain and TF;Prasad;J. Biomol. Struct. Dyn,2017

5. Tissue factor as a novel target for treatment of breast cancer;Cole;Oncologist,2013

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