A Hidden Active Site in the Potential Drug Target Mycobacterium tuberculosis dUTPase Is Accessible through Small Amplitude Protein Conformational Changes-Reference-Cited by-同舟云学术

A Hidden Active Site in the Potential Drug Target Mycobacterium tuberculosis dUTPase Is Accessible through Small Amplitude Protein Conformational Changes

Published:2016-12 Issue:51 Volume:291 Page:26320-26331
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Lopata Anna,Leveles Ibolya,Bendes Ábris Ádám,Viskolcz Béla,Vértessy Beáta G.,Jójárt Balázs,Tóth Judit

Funder

Országos Tudományos Kutatási Alapprogramok

International Center for Genetic Engineering and Biotechnology

Magyar Tudományos Akadémia

National Institutes of Health

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference66 articles.

1. UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke;Lee;Cell,2006

2. Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen;Gai;Cell,2004

3. Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism;Velankar;Cell,1999

4. Nucleotide switches in molecular motors: structural analysis of kinesins and myosins;Sablin;Curr. Opin Struct. Biol,2001

5. The polynucleotide ligase and RNA capping enzyme superfamily of covalent nucleotidyltransferases;Shuman;Curr. Opin Struct. Biol,2004

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Molecular analysis of dUTPase of Helicobacter pylori for identification of novel inhibitors using in silico studies;Journal of Biomolecular Structure and Dynamics;2023-08-17

2. Evolution of tunnels in α/β-hydrolase fold proteins – what can we learn from studying epoxide hydrolases?;2021-12-10

3. Substrate Tunnel Engineering Aided by X-ray Crystallography and Functional Dynamics Swaps the Function of MIO-Enzymes;ACS Catalysis;2021-03-30

4. Targeting a critical step in fungal hexosamine biosynthesis;Journal of Biological Chemistry;2020-06

5. Structural Insight into African Swine Fever Virus dUTPase Reveals a Novel Folding Pattern in the dUTPase Family;Journal of Virology;2020-01-31