Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling

Author:

Duggimpudi Sujitha,Kloetgen Andreas,Maney Sathish Kumar,Münch Philipp C.,Hezaveh Kebria,Shaykhalishahi Hamed,Hoyer Wolfgang,McHardy Alice C.,Lang Philipp A.,Borkhardt Arndt,Hoell Jessica I.

Funder

Heinrich-Heine-Universität Düsseldorf (HHU)

Deutsche Forschungsgemeinschaft (DFG)

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

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2. A novel gene, MSI2, encoding a putative RNA-binding protein is recurrently rearranged at disease progression of chronic myeloid leukemia and forms a fusion gene with HOXA9 as a result of the cryptic t(7;17)(p15;q23);Barbouti;Cancer Res,2003

3. Role of HOXA9 in leukemia: Dysregulation, cofactors and essential targets;Collins;Oncogene,2016

4. C/EBPα is an essential collaborator in Hoxa9/Meis1-mediated leukemogenesis;Collins;Proc. Natl. Acad. Sci. U.S.A,2014

5. DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia;Figueroa;Cancer Cell,2010

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