The balance of interleukin (IL)-6, IL-6·soluble IL-6 receptor (sIL-6R), and IL-6·sIL-6R·sgp130 complexes allows simultaneous classic and trans-signaling-Reference-Cited by-同舟云学术

The balance of interleukin (IL)-6, IL-6·soluble IL-6 receptor (sIL-6R), and IL-6·sIL-6R·sgp130 complexes allows simultaneous classic and trans-signaling

Published:2018-05 Issue:18 Volume:293 Page:6762-6775
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Baran Paul,Hansen Selina,Waetzig Georg H.,Akbarzadeh Mohammad,Lamertz Larissa,Huber Heinrich J.,Ahmadian M. Reza,Moll Jens M.,Scheller Jürgen

Funder

Deutsche Forschungsgemeinschaft (DFG)

Bundesministerium für Bildung und Forschung (BMBF)

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

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3. Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses;Jostock;Eur. J. Biochem,2001

4. Soluble interleukin-6 receptors released from T cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanism;Horiuchi;Eur. J. Immunol,1994

5. Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE);Matthews;J. Biol. Chem,2003

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