Glutamate–oxaloacetate transaminase activity promotes palmitate lipotoxicity in rat hepatocytes by enhancing anaplerosis and citric acid cycle flux-Reference-Cited by-同舟云学术

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Glutamate–oxaloacetate transaminase activity promotes palmitate lipotoxicity in rat hepatocytes by enhancing anaplerosis and citric acid cycle flux

Published:2019-03 Issue:9 Volume:294 Page:3081-3090
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Egnatchik Robert A.,Leamy Alexandra K.,Sacco Sarah A.,Cheah Yi Ern,Shiota Masakazu,Young Jamey D.

Funder

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

National Science Foundation

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference40 articles.

1. Alterations of hepatic ATP homeostasis and respiratory chain during development of non-alcoholic steatohepatitis in a rodent model;Serviddio;Eur. J. Clin. Invest,2008

2. Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis;Perez-Carreras;Hepatology,2003

3. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities;Sanyal;Gastroenterology,2001

4. Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver;Satapati;J. Lipid Res,2012

5. Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease;Sunny;Cell Metab,2011

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