Membrane Topology and Retention of Microsomal Aldehyde Dehydrogenase in the Endoplasmic Reticulum
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
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3. A short amino-terminal segment of microsomal cytochrome P-450 functions both as an insertion signal and as a stop-transfer sequence.
4. Signals for the incorporation and orientation of cytochrome P450 in the endoplasmic reticulum membrane.
5. An N-terminal glycosylation signal on cytochrome P450 is restricted to the endoplasmic reticulum in a luminal orientation.
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