Importance of the P4′ Residue in Human Granzyme B Inhibitors and Substrates Revealed by Scanning Mutagenesis of the Proteinase Inhibitor 9 Reactive Center Loop-Reference-Cited by-同舟云学术

Importance of the P4′ Residue in Human Granzyme B Inhibitors and Substrates Revealed by Scanning Mutagenesis of the Proteinase Inhibitor 9 Reactive Center Loop

Published:2001-01 Issue:18 Volume:276 Page:15177-15184
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Sun Jiuru,Whisstock James C.,Harriott Patrick,Walker Brian,Novak Andrea,Thompson Philip E.,Smith A. Ian,Bird Phillip I.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference48 articles.

1. Cytotoxic Cells: Basic Mechanisms and Medical Applications;Trapani,2000

2. Proteases and Cell-Mediated Cytotoxicity

3. New Paradigm for Lymphocyte Granule-mediated Cytotoxicity

4. Entry and Trafficking of Granzyme B in Target Cells During Granzyme B-Perforin–Mediated Apoptosis

5. Granzyme B Directly and Efficiently Cleaves Several Downstream Caspase Substrates: Implications for CTL-Induced Apoptosis

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