3-Nitropropionic Acid Is a Suicide Inhibitor of Mitochondrial Respiration That, upon Oxidation by Complex II, Forms a Covalent Adduct with a Catalytic Base Arginine in the Active Site of the Enzyme-Reference-Cited by-同舟云学术

3-Nitropropionic Acid Is a Suicide Inhibitor of Mitochondrial Respiration That, upon Oxidation by Complex II, Forms a Covalent Adduct with a Catalytic Base Arginine in the Active Site of the Enzyme

Published:2006-03 Issue:9 Volume:281 Page:5965-5972
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Huang Li-shar,Sun Gang,Cobessi David,Wang Andy C.,Shen John T.,Tung Eric Y.,Anderson Vernon E.,Berry Edward A.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference49 articles.

1. Moldy Sugarcane Poisoning— A Case Report with a Brief Review

2. Metabolism of the plant toxins nitropropionic acid and nitropropanol by ruminal microorganisms

3. Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid

4. Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia

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