Pancreatic Polypeptide Is Recognized by Two Hydrophobic Domains of the Human Y4 Receptor Binding Pocket-Reference-Cited by-同舟云学术

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Pancreatic Polypeptide Is Recognized by Two Hydrophobic Domains of the Human Y4 Receptor Binding Pocket

Published:2014-02 Issue:9 Volume:289 Page:5846-5859
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Pedragosa-Badia Xavier,Sliwoski Gregory R.,Dong Nguyen Elizabeth,Lindner Diana,Stichel Jan,Kaufmann Kristian W.,Meiler Jens,Beck-Sickinger Annette G.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference58 articles.

1. Tools for GPCR drug discovery;Zhang;Acta Pharmacol. Sin,2012

2. Molecular signatures of G-protein-coupled receptors;Venkatakrishnan;Nature,2013

3. Structure-activity studies of RFamide peptides reveal subtype-selective activation of neuropeptide FF1 and FF2 receptors;Findeisen;Chem. Med. Chem,2011

4. Coexpression of Y1, Y2, and Y4 receptors in smooth muscle coupled to distinct signaling pathways;Misra;J. Pharmacol. Exp. Ther,2004

5. Neuropeptide Y receptors: How to get subtype selectivity;Pedragosa Badia;Front. Endocrinol,2013

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1. Illuminating the neuropeptide Y4 receptor and its ligand pancreatic polypeptide from a structural, functional, and therapeutic perspective;Neuropeptides;2024-06

2. Novel enzyme‐resistant pancreatic polypeptide analogs evoke pancreatic beta‐cell rest, enhance islet cell turnover, and inhibit food intake in mice;BioFactors;2024-04-18

3. Structure–Activity Relationship Study of the High-Affinity Neuropeptide Y₄ Receptor Positive Allosteric Modulator VU0506013;Journal of Medicinal Chemistry;2023-06-20

4. Pancreatic polypeptide revisited: Potential therapeutic effects in obesity-diabetes;Peptides;2023-02

5. Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors;Science Advances;2022-05-06

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