Positional Scanning Mutagenesis of α-Conotoxin PeIA Identifies Critical Residues That Confer Potency and Selectivity for α6/α3β2β3 and α3β2 Nicotinic Acetylcholine Receptors
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference47 articles.
1. Mammalian nicotinic acetylcholine receptors. From structure to function;Albuquerque;Physiol. Rev,2009
2. Distribution and pharmacology of α6-containing nicotinic acetylcholine receptors analyzed with mutant mice;Champtiaux;J. Neurosci,2002
3. Localization of nAChR subunit mRNAs in the brain of Macaca mulatta;Han;Eur. J. Neurosci,2000
4. Nicotinic acetylcholine receptor subtypes involved in facilitation of GABAergic inhibition in mouse superficial superior colliculus;Endo;J. Neurophysiol,2005
5. Transport of multiple nicotinic acetylcholine receptors in the rat optic nerve. High densities of receptors containing α6 and β3 subunits;Cox;J. Neurochem,2008
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