A Chemogenomic Screen in Saccharomyces cerevisiae Uncovers a Primary Role for the Mitochondria in Farnesol Toxicity and Its Regulation by the Pkc1 Pathway-Reference-Cited by-同舟云学术

A Chemogenomic Screen in Saccharomyces cerevisiae Uncovers a Primary Role for the Mitochondria in Farnesol Toxicity and Its Regulation by the Pkc1 Pathway

Published:2007-02 Issue:7 Volume:282 Page:4868-4874
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Fairn Gregory D.,MacDonald Kendra,McMaster Christopher R.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference34 articles.

1. Differences in sensitivity to farnesol toxicity between neoplastically- and non-neoplastically-derived cells in culture

2. Preferential induction of apoptosis of leukaemic cells by farnesol

3. Inhibition of Phosphatidylcholine Biosynthesis following Induction of Apoptosis in HL-60 Cells

4. Competitive Inhibition of Choline Phosphotransferase by Geranylgeraniol and Farnesol Inhibits Phosphatidylcholine Synthesis and Induces Apoptosis in Human Lung Adenocarcinoma A549 Cells

5. Uncoupling Farnesol-induced Apoptosis from Its Inhibition of Phosphatidylcholine Synthesis

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