The Farnesyl Transferase Inhibitor (FTI) SCH66336 (lonafarnib) Inhibits Rheb Farnesylation and mTOR Signaling
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference62 articles.
1. rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein.
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4. Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
5. Insulin Activation of Rheb, a Mediator of mTOR/S6K/4E-BP Signaling, Is Inhibited by TSC1 and 2
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