HRX Leukemic Fusion Proteins Form a Heterocomplex with the Leukemia-associated Protein SET and Protein Phosphatase 2A
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference68 articles.
1. Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias
2. HRX involvement in de novo and secondary leukemias with diverse chromosome 11q23 abnormalities [see comments]
3. A trithorax–like gene is interrupted by chromosome 11q23 translocations in acute leukaemias
4. The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene
5. Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.
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1. PP2A complex disruptor SET prompts widespread hypertranscription of growth-essential genes in the pancreatic cancer cells;Science Advances;2024-01-26
2. SET-PP2A complex as a new therapeutic target in KMT2A (MLL) rearranged AML;Oncogene;2023-10-27
3. SET-PP2A complex as a new therapeutic target in KMT2A (MLL) rearranged AML.;2023-02-16
4. Histone acetylation insulator SET orchestrates PP2A inhibition and super-enhancer activation;2023-01-17
5. Thirty years of SET/TAF1β/I2PP2A: from the identification of the biological functions to its implications in cancer and Alzheimer’s disease;Bioscience Reports;2022-11
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