Identification of Glu-268 as the Catalytic Nucleophile of Human Lysosomal β-Galactosidase Precursor by Mass Spectrometry
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference13 articles.
1. Characteristics of the β-galactosidase-carboxypeptidase complex in GM1-gangliosidosis and β-galactosialidosis fibroblasts
2. Kinetic mechanism and characterization of human β-galactosidase precursor secreted by permanently transfected Chinese hamster ovary cells
3. Early proteolytic cleavage with loss of a C-terminal fragment underlies altered processing of the β-galactosidase precursor in galactosialidosis
4. Catalytic mechanism of enzymic glycosyl transfer
5. In vivo inhibition of β-glucosidase and β-mannosidase activity in rats by 2-deoxy-2-fluoro-β-glycosyl fluorides and recovery of activity in vivo and in vitro
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