The Deviant ATP-binding Site of the Multidrug Efflux Pump Pdr5 Plays an Active Role in the Transport Cycle-Reference-Cited by-同舟云学术

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The Deviant ATP-binding Site of the Multidrug Efflux Pump Pdr5 Plays an Active Role in the Transport Cycle

Published:2013-10 Issue:42 Volume:288 Page:30420-30431
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Furman Christopher,Mehla Jitender,Ananthaswamy Neeti,Arya Nidhi,Kulesh Bridget,Kovach Ildiko,Ambudkar Suresh V.,Golin John

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference33 articles.

1. ABC transporters. A riddle wrapped in a mystery inside an enigma;Jones;Trends Biochem. Sci,2009

2. Normal gating of CFTR requires ATP binding to both nucleotide-binding domains and hydrolysis at the second nucleotide-binding domain;Berger;Proc. Natl. Acad. Sci. U.S.A,2005

3. ATP binding to the first nucleotide-binding domain of the multidrug resistance-associated protein plays a regulatory role at low nucleotide concentration, whereas ATP hydrolysis at the second plays a dominant role in ATP-dependent leukotriene C4 transport;Hou;J. Biol. Chem,2003

4. Structure and function of ABC transporters. The ATP switch provides flexible control;Linton;Pflugers Arch,2007

5. CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains;Vergani;Nature,2005

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1. The noncanonical nucleotide binding site 1 of the bile salt export pump is optimized for proper function of the transporter;Cell Biology International;2024-02-08

2. Structure, function, and inhibition of catalytically asymmetric ABC transporters: Lessons from the PDR subfamily;Drug Resistance Updates;2023-11

3. Residues forming the gating regions of asymmetric multidrug transporter Pdr5 also play roles in conformational switching and protein folding;Journal of Biological Chemistry;2022-12

4. A New Twist in ABC Transporter Mediated Multidrug Resistance – Pdr5 is a Drug/proton Co-transporter;Journal of Molecular Biology;2022-07

5. How fungal multidrug transporters mediate hyper resistance through DNA amplification and mutation;Molecular Microbiology;2022-06-06

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