Fused in Sarcoma (FUS) Protein Lacking Nuclear Localization Signal (NLS) and Major RNA Binding Motifs Triggers Proteinopathy and Severe Motor Phenotype in Transgenic Mice

Author:

Shelkovnikova Tatyana A.,Peters Owen M.,Deykin Alexey V.,Connor-Robson Natalie,Robinson Hannah,Ustyugov Alexey A.,Bachurin Sergey O.,Ermolkevich Tatyana G.,Goldman Igor L.,Sadchikova Elena R.,Kovrazhkina Elena A.,Skvortsova Veronica I.,Ling Shuo-Chien,Da Cruz Sandrine,Parone Philippe A.,Buchman Vladimir L.,Ninkina Natalia N.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference24 articles.

1. Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis;Kwiatkowski;Science,2009

2. Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6;Vance;Science,2009

3. FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis;Deng;Ann. Neurol,2010

4. A new subtype of frontotemporal lobar degeneration with FUS pathology;Neumann;Brain,2009

5. Abundant FUS-immunoreactive pathology in neuronal intermediate filament inclusion disease;Neumann;Acta Neuropathol,2009

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