The Clustered, Regularly Interspaced, Short Palindromic Repeats-associated Endonuclease 9 (CRISPR/Cas9)-created MDM2 T309G Mutation Enhances Vitreous-induced Expression of MDM2 and Proliferation and Survival of Cells

Author:

Duan Yajian,Ma Gaoen,Huang Xionggao,D'Amore Patricia A.,Zhang Feng,Lei Hetian

Funder

National Eye Institute

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference47 articles.

1. Proliferative vitreoretinopathy after eye injuries: an overexpression of growth factors and cytokines leading to a retinal keloid;Morescalchi;Mediators Inflamm,2013

2. The T309G MDM2 gene polymorphism is a novel risk factor for proliferative vitreoretinopathy;Pastor-Idoate;PLoS ONE,2013

3. A novel function of p53: a gatekeeper of retinal detachment;Lei;Am. J. Pathol,2012

4. RasGAP promotes autophagy and thereby suppresses platelet-derived growth factor receptor-mediated signaling events, cellular responses, and pathology;Lei;Mol. Cell Biol,2015

5. Epithelial-mesenchymal transition in proliferative vitreoretinopathy: intermediate filament protein expression in retinal pigment epithelial cells;Casaroli-Marano;Invest. Ophthalmol. Vis. Sci,1999

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