Unraveling the structural basis of grazoprevir potency against clinically relevant substitutions in hepatitis C virus NS3/4A protease from genotype 1a

Author:

Guo Zhuyan,Black Stuart,Hu Yuan,McMonagle Patricia,Ingravallo Paul,Chase Robert,Curry Stephanie,Asante-Appiah Ernest

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference28 articles.

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2. Global distribution and prevalence of hepatitis C virus genotypes;Messina;Hepatology,2015

3. An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases;Ghany;Hepatology,2011

4. World Health Organization. (2016) Guidelines for the screening, care and treatment of persons with chronic hepatitis C infection updated version. April 2016, WHO Document Production Services, Geneva, Switzerland.

5. Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3′-nontranslated region are essential for virus replication in vivo;Kolykhalov;J. Virol,2000

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