Introduction of a Fluorine Atom at C3 of 3-Deazauridine Shifts Its Antimetabolic Activity from Inhibition of CTP Synthetase to Inhibition of Orotidylate Decarboxylase, an Early Event in the de Novo Pyrimidine Nucleotide Biosynthesis Pathway-Reference-Cited by-同舟云学术

Introduction of a Fluorine Atom at C3 of 3-Deazauridine Shifts Its Antimetabolic Activity from Inhibition of CTP Synthetase to Inhibition of Orotidylate Decarboxylase, an Early Event in the de Novo Pyrimidine Nucleotide Biosynthesis Pathway

Published:2012-08 Issue:36 Volume:287 Page:30444-30454
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Balzarini Jan,Gago Federico,Kulik Wim,van Kuilenburg André B.P.,Karlsson Anna,Peterson Matt A.,Robins Morris J.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

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