Engineering of a Recombinant Vitamin K-dependent γ-Carboxylation System with Enhanced γ-Carboxyglutamic Acid Forming Capacity
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
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1. A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase;Nature Communications;2023-02-14
2. Effect of prepropeptide replacement on γ-carboxylation and activity of recombinant coagulation factor IX;Biotechnology Letters;2022-06-22
3. Vitamin K-Dependent Protein Activation: Normal Gamma-Glutamyl Carboxylation and Disruption in Disease;International Journal of Molecular Sciences;2022-05-20
4. Generation of hyperfunctional recombinant human factor IX variants expressed in human cell line SK-Hep-1;Biotechnology Letters;2020-11-01
5. A cell-based high-throughput screen identifies drugs that cause bleeding disorders by off-targeting the vitamin K cycle;Blood;2020-08-13
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