Novel drug discovery platform for spinocerebellar ataxia, using fluorescence technology targeting β-III-spectrin
Author:
Funder
National Institutes of Health
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference49 articles.
1. A novel missense mutation in the spectrin beta nonerythrocytic 2 gene likely associated with spinocerebellar ataxia type 5;Liu;Chin. Med. J. (Engl.),2016
2. Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis;Kaplan;Nat. Genet.,2000
3. Mutational and biological analysis of alpha-actinin-4 in focal segmental glomerulosclerosis;Weins;J. Am. Soc. Nephrol.,2005
4. Congenital macrothrombocytopenia-linked mutations in the actin-binding domain of alpha-actinin-1 enhance F-actin association;Murphy;FEBS Lett.,2016
5. Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders;Clark;Hum. Mol. Genet.,2009
Cited by 9 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. A single-cell transcriptomic analysis of the mouse hippocampus after voluntary exercise;2023-08-05
2. HTS driven by fluorescence lifetime detection of FRET identifies activators and inhibitors of cardiac myosin;SLAS Discovery;2023-07
3. Fluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators;Scientific Reports;2023-07-01
4. Early-phase drug discovery of β-III-spectrin actin-binding modulators for treatment of spinocerebellar ataxia type 5;Journal of Biological Chemistry;2023-03
5. FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators;2023-02-28
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3