Acquisition of exogenous fatty acids renders apicoplast-based biosynthesis dispensable in tachyzoites of Toxoplasma-Reference-Cited by-同舟云学术

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Acquisition of exogenous fatty acids renders apicoplast-based biosynthesis dispensable in tachyzoites of Toxoplasma

Published:2020-05 Issue:22 Volume:295 Page:7743-7752
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Liang Xiaohan,Cui Jianmin,Yang Xuke,Xia Ningbo,Li Yaqiong,Zhao Junlong,Gupta Nishith^ORCID,Shen Bang^ORCID

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Fundamental Research Funds for Central Universities in China

German Research Foundation

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference38 articles.

1. Foodborne toxoplasmosis;Jones;Clin. Infect. Dis,2012

2. Toxoplasma gondii: epidemiology, feline clinical aspects, and prevention;Elmore;Trends Parasitol,2010

3. Pyruvate homeostasis as a determinant of parasite growth and metabolic plasticity in Toxoplasma gondii;Xia;MBio,2019

4. Mitochondrial metabolism of glucose and glutamine is required for intracellular growth of Toxoplasma gondii;MacRae;Cell Host Microbe,2012

5. Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis;Blume;Proc. Natl. Acad. Sci. U.S.A,2009

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1. TgGloL is an atypical glyoxalase/VOC domain-containing apicoplast protein that is important for the growth ofToxoplasma;2024-09-04

2. A pyruvate transporter in the apicoplast of apicomplexan parasites;Proceedings of the National Academy of Sciences;2024-06-12

3. The acyl-CoA synthetase Tg ACS1 allows neutral lipid metabolism and extracellular motility in Toxoplasma gondii through relocation via its peroxisomal targeting sequence (PTS) under low nutrient conditions;mBio;2024-04-10

4. The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival;eLife;2024-03-19

5. Lipid metabolism: the potential targets for toxoplasmosis treatment;Parasites & Vectors;2024-03-06

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