The RAS-interacting chaperone UNC119 drives the RASSF6–MDM2–p53 axis and antagonizes RAS-mediated malignant transformation

Author:

Shimizu TakanobuORCID,Nakamura TakeshiORCID,Inaba HironoriORCID,Iwasa Hiroaki,Maruyama JunichiORCID,Arimoto-Matsuzaki Kyoko,Nakata Takao,Nishina Hiroshi,Hata YutakaORCID

Funder

MEXT | Japan Society for the Promotion of Science

Mitsubishi Foundation

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference48 articles.

1. HRG4 (UNC119) mutation found in cone-rod dystrophy causes retinal degeneration in a transgenic model;Kobayashi;Invest. Ophthalmol. Vis. Sci,2000

2. An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium;Wright;Genes Dev,2011

3. Cloning of the cDNA for a novel photoreceptor protein;Higashide;J. Biol. Chem,1996

4. Mammalian orthologs of C. elegans unc-119 highly expressed in photoreceptors;Swanson;Invest. Ophthalmol. Vis. Sci,1998

5. Photoreceptor synaptic protein HRG4 (UNC119) interacts with ARL2 via a putative conserved domain;Kobayashi;FEBS Lett,2003

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