Chemokine receptor CXCR4 oligomerization is disrupted selectively by the antagonist ligand IT1t

Author:

Ward Richard J.,Pediani John D.,Marsango Sara,Jolly Richard,Stoneman Michael R.ORCID,Biener GabrielORCID,Handel Tracy M.,Raicu ValericăORCID,Milligan GraemeORCID

Funder

Medical Research Council

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference44 articles.

1. Cryo-EM structures of GPCRs coupled to Gs, Gi and Go;García-Nafría;Mol. Cell Endocrinol.,2019

2. Structural biology of G protein-coupled receptor signaling complexes;Zhou;Protein Sci.,2019

3. GPCR homo-oligomerization;Milligan;Curr. Opin. Cell Biol.,2019

4. Prediction and Targeting of interaction interfaces in G-protein coupled receptor oligomers;Schiedel;Curr. Top Med. Chem.,2018

5. An update on the physiological and therapeutic relevance of GPCR oligomers;Farran;Pharmacol. Res.,2017

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