Inhibition of the ATR kinase enhances 5-FU sensitivity independently of nonhomologous end-joining and homologous recombination repair pathways-Reference-Cited by-同舟云学术

Inhibition of the ATR kinase enhances 5-FU sensitivity independently of nonhomologous end-joining and homologous recombination repair pathways

Published:2020-09 Issue:37 Volume:295 Page:12946-12961
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Ito Soichiro S.^ORCID,Nakagawa Yosuke,Matsubayashi Masaya^ORCID,Sakaguchi Yoshihiko M.,Kobashigawa Shinko,Matsui Takeshi K.,Nanaura Hitoki^ORCID,Nakanishi Mari,Kitayoshi Fumika,Kikuchi Sotaro,Kajihara Atsuhisa,Tamaki Shigehiro,Sugie Kazuma^ORCID,Kashino Genro,Takahashi Akihisa,Hasegawa Masatoshi,Mori Eiichiro^ORCID,Kirita Tadaaki

Funder

MEXT | Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference72 articles.

1. 5-fluorouracil: mechanisms of action and clinical strategies;Longley;Nat. Rev. Cancer,2003

2. 5-FU metabolism in cancer and orally-administrable 5-FU drugs;Miura;Cancers,2010

3. The BRCA2 gene is a potential molecular target during 5-fluorouracil therapy in human oral cancer cells;Nakagawa;Oncol. Rep,2014

4. Participation of DNA repair in the response to 5-fluorouracil;Wyatt;Cell Mol. Life Sci,2009

5. DNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets;Li;Br. J. Pharmacol,2009

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